Today, DMT-based psychedelic therapeutic products offer an interesting avenue for researchers to explore in the treatment of addiction and substance use disorders. It’s actually been proposed that DMT can increase the brain’s neuro-plasticity and even promote the formation of new neural connections, or synapses.
Furthermore, animal studies have shown that DMT promotes neuro-plasticity, neuronal growth and increased synaptic connections – for patients who struggle with mood and addiction disorders, DMT therapy offers the potential to regulate brain pathways and possibly correct the seemingly untreatable problems.
Entheon Biomedical CEO, Timothy Ko has spoken extensively on the incredible healing potential of DMT-based treatments. Mr. Ko has a personal connection to this field of research as his brother, who struggled with addiction to opioids among other substances, tragically passed away.
According to Mr. Ko, psychedelic usage can open up components of openness and self-transcendence in patients: “From a neuro-plasticity perspective, it allows the user to face more difficult elements of thinking… Psychedelics are known to change one’s relationship to the default mode network so that it increases brain entropy and allows for more connectivity.”
Timothy Ko and his company, Entheon Biomedical (CSE: ENBI, OTC: ENTBF), are on a quest to develop state-of-the-art psychedelic medicines to treat addiction disorders. Mr. Ko’s personal connection to the tragedy of drug addiction spurred him to found Entheon so that untold numbers of patients and their families won’t have to suffer the same loss that he did.
As Mr. Ko has pointed out, drug addiction isn’t limited to illegal drugs, as 90,000 people die every year from alcoholism. Even beyond the loss of life, Timothy explains that families are torn to pieces, children are affected, and the economic costs are in the untold billions of dollars.
Entheon Biomedical is poised to uncover solutions where conventional treatments simply aren’t effective. Shockingly, traditional addiction treatment centers have efficacy rates as low as 5%, while only 10% of patients will receive any treatment at all.
To tackle these problems, Timothy Ko felt a responsibility to provide new options for patients whose challenges weren’t being properly addressed by the currently available treatments. He found that the solution with the greatest potential is the continuous infusion of DMT over time for the treatment of drug addiction, housed within a supportive therapeutic framework.
It’s a novel approach to addiction treatment as psychedelics help to create massively profound, insightful, and powerful experiences – and the DMT molecule has shown great potential in achieving this. Entheon is developing a safe and medically supported way to administer DMT to those who suffer from drug addiction.
For Timothy Ko and Entheon Biomedical, there are no “lost causes” – only new options to explore and possibilities to uncover. Entheon exists to invert the recovery ratio in addiction disorders, turning the seemingly “untreatable case” from the rule to the exception.
For biopharmaceutical companies, securing patents for treatments and getting regulatory approval are among the most important milestones. Fortunately, Entheon has signed a formal partnership agreement with Contract Research Organization, CHDR and clinical trials are scheduled to begin in late summer 2021.
Entheon has also filed provisional patents in connection with DMT therapy as an addiction treatment, and the company intends to pursue full FDA, Health Canada, and EMA regulatory approval. This isn’t just a necessary part of the process, but will also provide enhanced value to long-term stakeholders as biotech investments can increase quickly in value as these milestones are achieved.
For Entheon, solid science will inevitably lead to the achievement of these goals. Mr. Ko explains that Entheon’s approach is to take the psychedelics-focused research that has been gleaned over decades, apply this knowledge to current scientific studies, compile the data, and present it to regulators to show that DMT has a very strong safety and efficacy profile.
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