In the U.S., multiple reforms were afoot with the November 3rd elections. Oregon’s Measure 110: Addiction Recovery Centers (which easily passed by a 58.5% “yes” vote) decriminalized the personal possession for adults of a variety of drugs, while also allocating state funds towards health assessments, addiction treatments, harm-reduction efforts, and other services for people with addiction disorders.
Also in Oregon, the voters overwhelmingly passed Measure 109: Legalize Psilocybin by a 56% majority; this measure will mandate that state health authorities create a program for administering psilocybin products to people 21 and older.
Meanwhile, Washington, D.C.’s Initiative 81: The Entheogenic Plants and Fungus Measure – which passed by an overwhelming 76% “yes” vote – declared that police must now treat the non-commercial cultivation, distribution, possession, and use of entheogenic plants and fungi (including DMT and psilocybin) among the lowest law enforcement priorities.
But if any region in the U.S. could be considered the “Amsterdam of America,” it would probably be Denver, Colorado. Back in May of 2019, Denver voters passed Initiative 301, a ballot measure to decriminalize psilocybin and direct local law enforcement to give psychedelic mushrooms the lowest arrest priority for adults 21 and older.
So, what’s the next step for regulators and for the medical community in pursuing better treatments for struggling patients in North America and worldwide? We’ve seen the groundswell of support for research and psychedelics – this includes not just “magic mushrooms” but also, and perhaps even more compellingly, a high-potential medical alternative known as DMT.
Researchers are looking closely into treatment solutions that involve therapy along with what’s known as dimethyltryptamine or DMT. Brews containing ayahuasca, which has DMT in it, have been used for many centuries as a way to treat mood disorders, addiction, and psychological problems.
Entheon Biomedical is poised to uncover solutions where conventional treatments simply aren’t effective. Shockingly, traditional addiction treatment centers have efficacy rates as low as 5%, while only 10% of patients will receive any treatment at all.
To tackle these problems, Timothy Ko felt a responsibility to provide new options for patients whose challenges weren’t being properly addressed by the currently available treatments. He found that the solution with the greatest potential is the continuous infusion of DMT over time for the treatment of drug addiction, housed within a supportive therapeutic framework.
It’s a novel approach to addiction treatment as psychedelics help to create massively profound, insightful, and powerful experiences – and the DMT molecule has shown great potential in achieving this. Entheon is developing a safe and medically supported way to administer DMT to those who suffer from drug addiction.
For Timothy Ko and Entheon Biomedical, there are no “lost causes” – only new options to explore and possibilities to uncover. Entheon exists to invert the recovery ratio in addiction disorders, turning the seemingly “untreatable case” from the rule to the exception.
For biopharmaceutical companies, securing patents for treatments and getting regulatory approval are among the most important milestones. Fortunately, Entheon has signed a formal partnership agreement with Contract Research Organization, CHDR and clinical trials are scheduled to begin in late summer 2021.
Entheon has also filed provisional patents in connection with DMT therapy as an addiction treatment, and the company intends to pursue full FDA, Health Canada, and EMA regulatory approval. This isn’t just a necessary part of the process, but will also provide enhanced value to long-term stakeholders as biotech investments can increase quickly in value as these milestones are achieved.
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